Advances in The SELEX Technique and Aptamers / 生物化学与生物物理进展
Progress in Biochemistry and Biophysics
;
(12)2006.
Artículo
en Chino
| WPRIM
| ID: wpr-586471
ABSTRACT
Aptamers are short single-stranded nucleic acid ligands that are capable of binding almost any targets with low nano- to picomolar affinities and exceptional specificities. They are selected out of a large combinatorial oligonucleotide library through an in vitro evolution process termed SELEX (systematic evolution of ligands by exponential enrichment). The unique advantages of high-throughput screening technique and aptamers in precise recognition as well as easiness to synthesis and modification bring aptamers a bright prospect in analytical chemistry, biology and medicine research. The recent advances in the SELEX technique and aptamers are reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Progress in Biochemistry and Biophysics
Año:
2006
Tipo del documento:
Artículo
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