The prediction of neonatal respiratory distress syndrome by stable microbubble test and surfactant protein A level in gastric aspirate / 中华检验医学杂志

ABSTRACT

Objective To investigate the application of stable microbubble test ( SMT) and surfactant protein A ( SP-A) level in gastric aspirate in predicting neonatal respiratory distress syndrome ( RDS). Methods One hundred and ten high-risk preterm infants within 1 hour after birth, with gestational age between 24 and 36 weeks, birth weight between 1 160 g and 2 010 g were admitted in the study. The gastric secretion of 1-2 ml was collected during routine aspiration for SMT. At the same time SP-A level was measured by enzyme linked immuno sorbent assay. Results The SMT count and SP-A level in preterm infants with RDS were lower than those of infants without RDS [SMT (5. 7?2. 4) microbubbleg/mm2( mb/ mm2) vs. (12.4?6.0) mb/mm2, t = 8. 355,P