Semi-quantitative Procalcitonin Assay in Critically ill Patients with Respiratory infections / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 205-211, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-58893
ABSTRACT
BACKGROUND:
Serum procalcitonin level has been considered prognostic during sepsis and septic shock. We investigated the significance of procalcitonin in critically ill patients with respiratory infections.METHODS:
The patients who had radiographically diagnosed diffuse lung infiltrations were enrolled on a prospective basis. Bronchoalveolar lavage (BAL) fluid for the purpose of quantitative cultures (> or =10(4) cfu/mL) was obtained from all patients. Serum procalcitonin levels determined by PCT-Q kit were measured on BAL day and classified as follows; 10.0 ng/mL. We analyzed the patient's characteristics according to outcome; favorable or unfavorable, defined as death.RESULTS:
Patients from the following categories were included medical 17 (47.2%), surgical 9 (25%), and burned 10 (27.8%). APACHE II scores on admission to intensive care unit were 11.5+/-6.89 and 11 (30.6%) had unfavorable outcomes. A procalcitonin level > or =0.5 ng/mL was in 17 (47.2%) of all. On univariate analysis, the frequencies of burn injury, mechanical ventilation, multiple organ failure, and a procalcitonin level > or =0.5 ng/mL were more often increased in patients with unfavorable outcomes than in those with favorable outcomes (p or =0.5 ng/mL was more sensitive in predicting VAP than unfavorable outcome.CONCLUSION:
A higher procalcitonin level seems to be associated with VAP, but further study is required to know that procalcitonin would be a prognostic marker in critically ill patients with respiratory infections.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Precursores de Proteínas
/
Respiración Artificial
/
Infecciones del Sistema Respiratorio
/
Choque Séptico
/
Quemaduras
/
Calcitonina
/
Análisis Multivariante
/
Estudios Prospectivos
/
Enfermedad Crítica
/
Sepsis
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Año:
2009
Tipo del documento:
Artículo
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