Pityriasis Lichenoides-like Mycosis Fungoides: Clinical and Histologic Features and Response to Phototherapy
Annals of Dermatology
;
: 540-547, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-59037
ABSTRACT
BACKGROUND:
Pityriasis lichenoides (PL)-like skin lesions rarely appear as a specific manifestation of mycosis fungoides (MF).OBJECTIVE:
We investigated the clinicopathological features, immunophenotypes, and treatments of PL-like MF.METHODS:
This study included 15 patients with PL-like lesions selected from a population of 316 patients diagnosed with MF at one institution.RESULTS:
The patients were between 4 and 59 years of age. Four patients were older than 20 years of age. All of the patients had early-stage MF. In all patients, the atypical lymphocytic infiltrate had a perivascular distribution with epidermotropism. The CD4/CD8 ratio was <1 in 12 patients. Thirteen patients were treated with either narrowband ultraviolet B (NBUVB) or psoralen+ultraviolet A (PUVA), and all of them had complete responses.CONCLUSION:
PL-like MF appears to have a favorable prognosis and occurrence of this variant in adults is uncommon. MF should be suspected in the case of a PL-like skin eruption. Therefore, biopsy is required to confirm the diagnosis of PL-like MF, and NBUVB is a clinically effective treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fototerapia
/
Pitiriasis
/
Pronóstico
/
Piel
/
Biopsia
/
Micosis Fungoide
/
Pitiriasis Liquenoide
/
Diagnóstico
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Adulto
/
Humanos
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2016
Tipo del documento:
Artículo
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