Granulocyte-macrophage colony-stimulating factor down-regulates rat thyroid C cells / 医学研究生学报
Journal of Medical Postgraduates
;
(12)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-590461
ABSTRACT
Objective:
To investigate the influence of the granulocyte-macrophage colony-stimulating factor(GM-CSF) on rat thyroid parafollicular cells(C cells).Methods:
A total of 48 healthy SD rats were randomly and equally divided into a control group,a low dose group(GM-CSF 10 ?g/kg?d-1) and a high dose group(GM-CSF 50 ?g/kg?d-1).The latter two groups were treated by intraperitoneal administration of GM-CSF at their respective doses for 7 days,and then the thyroid parafollicular cells were stained by immunohishtochemical streptavidin-peroxidase(S-P) technique and their number counted.Results:
The number of C cells was(67.43 ? 13.73)in the high dose group,significantly smaller than that of the low dose group(85.97 ? 20.12)(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Medical Postgraduates
Año:
2003
Tipo del documento:
Artículo
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