Effect of -1 SNP on CCNH promoter activity / 基础医学与临床
Basic & Clinical Medicine
;
(12)2006.
Artículo
en Chino
| WPRIM
| ID: wpr-592054
ABSTRACT
Objective To study the effect of-1 site single nucleotide polymorphism(SNP) on CCNH gene promoter transcription activity.Methods PCR and site-directed mutagenesis technology were used to construct CCNH basic promoter and-1G mutate promoter.Dual-Luciferase Reporter assay system was used to detect the transcription activity of constructed promoter.Results In AD293 cells,the activity of-1G mutate type promoter was significantly lower than that of wild type-1T promoter(P
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Basic & Clinical Medicine
Año:
2006
Tipo del documento:
Artículo
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