Detection of PTEN gene promoter hypermethylation in lung cancer patients / 基础医学与临床
Basic & Clinical Medicine
;
(12)2006.
Artículo
en Chino
| WPRIM
| ID: wpr-592281
ABSTRACT
Objective To investigate the status and diagnostic value of aberrant phosphatase and tensin homology deleted on chromosometen(PTEN) gene promoter in tissues, peripheral plasma and BALF of lung cancer patients. Methods We analyzed the methylation of PTEN gene in tissues, peripheral plasma and BALF by methylation specific-PCR. Results The frequency of methylation of promoter of PTEN gene was 26.67%(12/45) in lung cancer tissues, 15.56%(7/45) in peripheral plasma, 22.22%(10/45) in BALF, no methylation product was found in lung tissues without cancer, normal plasma and BALF controls (P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Basic & Clinical Medicine
Año:
2006
Tipo del documento:
Artículo
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