Expression of muc-1 gene in non-small cell lung cancer and its clinical significance / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6)2006.
Artículo
en Chino
| WPRIM
| ID: wpr-593269
ABSTRACT
Objective To explore the relationship between expression of muc-1 gene in non-small cell lung cancer (NSCLC) tissues and lymph node metastasis and its clinical significance.Methods The expression of muc-1 gene in 36 specimens of NSCLC tissues and 10 normal lung tissues were determined by RT-PCR.Results muc-1 gene was positively expressed in 19 of 36 specimens of NSCLC tissues,the positive expression rate was 52.7%.The expression of muc-1 mRNA in NSCLC tissues was related to metastasis of lymph node(?2 =6.733,P0.05).The positive expression rate of muc-1 gene was higher in NSCLC tissues with lymph node metastasis(N0 10%,N1 58.82%,N2 88.9%).Conclusion The lymph node metastasis rate in NSCLC patients with muc-1 gene positive expression is higher,the detection of muc-1 gene expression can guide the prognosis and therapy of NSCLC patients after operation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Jilin University(Medicine Edition)
Año:
2006
Tipo del documento:
Artículo
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