Change of Antimicrobial Resistance among Proteus mirabilis Isolates / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To compare the changing trends of antibiotic resistance of Proteus mirabilis isolates.METHODS A total of 288 P.mirabilis isolates obtained from clinical patients in the First Affiliated Hospital of China Medical University between 2001-2006 were included in the study.K-B test was used to determine the susceptibility and the results were read based on National Committee for Clinical Laboratory Standards(NCCLS)of the USA.RESULTS The sensitivity of P.mirabilis isolates to imipenem,ceftazidime,cefotaxime,aztreonam,cefoperazone-tazobactam,cefepime,amikacin and piperacillin was from 74.5% to 95.2%,meanwhile there was a low sensitivity to ampicillin,cefazolin,ciprofloxacin,sulfamethoxazole co.and tetracycline,from 2.3% to 58.8%.CONCLUSIONS The result of antimicrobial susceptiveity test may instruct the applications of clinical antibiotics.