Advances of gene polymorphism correlated with hypercholesterolemia / 医学研究生学报

ABSTRACT

Hypercholesterolemia is an important risk factor of cardiovascular disease,which is related to complications and mortality of cardiovascular disease.A lot of researches show that some genes polymorphism was related to hypercholesterolemia.This paper introduces the hypercholesterolemia,including LDLR(low-density lipoprotein),apo(apolipoprotein) and PCSK9(proprotein convertase subtilisin kexin type 9),etc,and summed up the relationship between the genes polymorphism and hypercholesterolemia.