Monitoring of Drug-resistance in Klebsiella pneumoniae in a Oil Field Hospital / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate drug-resistance status of Klebsiella pneumoniae(KPN) among oil field staff-workers and provide the evidence for clinical application of antibiotics.METHODS Referring to the National Clinical Laboratory Operation Rules,KPN strains were isolated and identified.The drug-sensitivity testing was performed by K-B methods.The extended-spectrum-?-lactamases(ESBLs) producers were detected by double-disc synergy test and disc confirming test.RESULTS The 276 strains of KPN were mainly isolated from respiratory tract and urinary tract.The isolating rate of ESBLs-producing KPN was 37.0%.The results of susceptibility testing showed the drug-resistance to common antibiotics in ESBLs producers was generally higher than that in ESBLs nonproducer.There was no KPN resistant to imipenem and meropenem.CONCLUSIONS Drug-resistance status of KPN in a oil field hospital is very serious.We should strengthen monitoring and controlling of it.