Study on the floating characteristics of the calcium alginate-chi-tosan intragastric floating beads / 中国海洋药物
Chinese Journal of Marine Drugs
;
(6)2000.
Artículo
en Chino
| WPRIM
| ID: wpr-596784
ABSTRACT
Objective To prepare calcium alginate-chitosan intragastric floating beads and investigate the influences of various factors on the floating characteristics of beads.Methods Sodium alginate solution added with frother was slowly dripped into chitosan-calcium chloride solution added with acetic acid,calcium alginate-ehitosan intragastric floating beads were obtained after drying.The effects of frother,addition amount of acetic acid,the concentration of alginate solution,chitosan and calcium chloride solution on the floating characteristics of beads were investigated.Results Frother and addition amount of acetic acid were the main influence factors on the floating characteristics,and the concentrations of alginate solution, chitosan and calcium chloride solution also had some influences.Conclusion The calcium alginate-chitosan intragastrie floating beads with favorable floatability could be achieved through adjusting the formula,it laid a foundation for the furether development of the preparations in intragastric floating preparations.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Marine Drugs
Año:
2000
Tipo del documento:
Artículo
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