Advance of study in neonate with bilirubin encephalopathy / 国际儿科学杂志

ABSTRACT

As a challenging complication of neonatal jaundice, bilirubin encephalopathy can be subdivided into acute and chronic isoforms with the latter also named kernicterus. Its mechanism remains unclear. Its main sequelaes lie in auditory deficiency and dyskinesis. Brain stem auditory evoked potentials test is highly valued in the early diagnosis of kernicterus and the screening of auditory deficiency. MRI manifests symmetrical Tl-weighted signals on pallidum in acute phase and T2-weighted signals in chronic phase. The practical value of magnetic resonance spectrum yet demands further exploration.