Diagnostic significance of c-kit and Ki-67 expression in the baseal cell adenoma and adenoid cystic carcinom of salivary gland / 肿瘤研究与临床
Cancer Research and Clinic
; (6): 289-290,294, 2012.
Article
en Zh
| WPRIM
| ID: wpr-598117
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the expression of c-kit and Ki-67 in the basal cell adenoma(BCA)and adenoid cystic carcinoma (ACC) of salivary gland. Methods The expression of c-kit and Ki-67 was determined by immunohistochemistry method in BCA and ACC of salivary gland. Results The positive immuostaining of c-kit in BCA and ACC were 72.2 %(13/18) and 83.3 %(35/42),respectively, There was no significant difference in the expression of c-kit between the two tissues (x2=0.11,P>0.05).The expression of Ki-67 was significantly different between BCA[(3.72±1.41) %]and ACC[(23.81±10.19)%](t=14.145,P<0.01).Conclusion Detection of Ki-67 might be helpful to distinguish between BCA and ACC,but c-kit has no effect in differentiating BCA from ACC.
Texto completo:
1
Índice:
WPRIM
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
Cancer Research and Clinic
Año:
2012
Tipo del documento:
Article