Case-control study on the breast cancer risk factors of women in Karamay urban, Xinjian Uygur Autonomous Region / 肿瘤研究与临床

ABSTRACT

Objective To investigate the breast cancer risk factors in women of the Karamay Oilfield.Methods A case control study included 129 breast cancer patients and 129 normal healthy women.The logistic regression model was used for evaluating the breast cancer risk factors.Results The risk factors of breast cancer included a family history of breast cancer (OR =2.744,95 ％ CI =1.884-4.674),breast hyperplasia (OR =1.423,95 ％ CI =1.160-1.810),mastitis (OR =2.363,95 ％ CI =2.039-3.934),uterine fibroids (OR =1.623,95 ％ CI =1.263-2.024),abortion (OR =1.723,95 ％ CI =1.143-2.600),drinking (OR =1.243,95 ％ CI =1.040-1.483),trauma (OR =2.184,95 ％ CI =1.753-3.025),long-term exposure to ionizing radiation (OR =1.374,95 ％ CI =1.152-1.699); protective factors inculded increased age at menarche (OR =0.773,95 ％ CI =0.674-0.956),cumulative lactation time (OR =0.672,95 ％ CI =0.480-0.941),adhere to exercise (OR =0.572,95 ％ CI =0.391-0.837).Conclusion These 11 factors could be important factors for breast cancer risk in Karamay Oilfield women.