Clinical effectiveness observation of manipulation in treating early perimenopausal depression / 中国基层医药

ABSTRACT

Objective To observe the clinical effectiveness of manipulation combined psychological counse-ling in treating early perimenopausal depression.Methods 62 patients with early perimenopausal depression were selected,and randomized into the two groups according visiting sequence.The treatment group received manipulation combined psychological counseling therapy, and control group received fluoxetine therapy.The clinical effectiveness between two groups was compared.Results The total effective rate of the treatment and control group was 90.30%and 83.90%,respectively,there was significant difference between the two groups (P=0.707);the score of HAMD depression scale was (8.90 ±0.87)points vs (9.29 ±2.98)points post 6 weeks of therapy,and the score reduction rate was (53.74 ±2.86)points vs (51.95 ±15.03)points (t=-0.69,0.65;P=0.492,0.520,respectively).No obvious side adverse effect was seen in the treatment group,and nausea (5 cases),dizziness (4) and anorexia (7) was seen in the control group.Conclusion Manipulation combined psychological counseling therapy was similarly effective in treating early perimenopausal depression compared with fluoxetine,but associated with less adverse effect.