Study of IL-3 and other hematopoietic cytokines expression of human amnion-derived mesenchymal stem cells and its significance / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 732-734,738, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-601805
ABSTRACT
Objective To investigate the cytokine spectrum of cultured human amniotic-derived mesenchymal stem cells (A-MSC) for understanding its basis of molecular biology in hematopoietic in vitro.Methods Their hematopoietic cytokines expression was analyzed using RT-PCR in the mRNA level. Results It showed that in vitro subcultured human amniotic-derived mesenchymal stem cells were capable to express many important hematopoietic cytokines such as LIF, SCF, M-CSF, G-CSF, GM-CSF, IL-3, IL-6, IL-11 and so on. Conclusion Production of abundant of hematopoietic cytokines by human amniotic-derived mesenchymal stem cells may be effective for hematopoietic support and HSC transplantation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Leukemia & Lymphoma
Año:
2010
Tipo del documento:
Artículo
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