Role of sphingosine-1-phosphate receptor 1 in pain modulation / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 755-758,759, 2015.
Article
en Zh
| WPRIM
| ID: wpr-602045
Biblioteca responsable:
WPRO
ABSTRACT
Sphingosine-1-phosphate receptor 1(S1PR1) is a new member of G protein-coupled receptor family. A great body of data suggest S1PR1 is capable of regulating lots of downstream signaling molecules and cellular processes. It is found that S1P/S1PR1 plays an important role in the development and mainte-nance of pain. However, it is controversial whether activation of S1PR1 would enhance or attenuate pain. Here, recent studies <br> and current perspectives are discussed in order to better under-stand the biological and pathological roles of S1PR1 in pain mod-ulation.
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Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
2015
Tipo del documento:
Article