Rapid Identification and Determination of Gatifloxacin Injections by Raman Spectroscopy / 中国药师
China Pharmacist
;
(12): 1626-1628,1648, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-602082
ABSTRACT
Objective:
To develop a method for the rapid identification and determination of gatifloxacin injections by Raman spec-troscopy.Methods:
Raman spectroscopy was used as the method of identifying and determining gatifloxacin injections. The determina-tion conditions were as followsa micro Raman spectroscopy, excitation wavelength785nm, objective lens50X, laser power3mW, signal acquisition time60s.Results:
The result showed that the Raman spectroscopy could identify and determine gatifloxacin injec-tions, the content of gatifloxacin in the injections was respectively 99. 49%,97. 56% and 100. 2%(Specification10ml∶0. 2g), and 97. 75%, 94. 58% and 96. 25%(Specification2ml∶0. 1g), and there was no significant difference between the above determination results and the results from the HPLC method by t-test.Conclusion:
For the fast and nondestructive properties, the presented method can be developed as an analysis method for gatifloxacin injections.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
China Pharmacist
Año:
2014
Tipo del documento:
Artículo
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