Application of Micropure System on Calcifications Detection of Thyroid Nodules / 中国医科大学学报

ABSTRACT

Objective To evaluate the ability of micropure system on calcifications detection of thyroid nodules. Methods A total of 63 patients with thyroid nodules that prepared for surgery were detected by micropure system and gray?scale ultrasound imaging,respectively. Results Among the 87 lesions removed with surgery,there were 72 benign lesions and 15 malignant ones. For the coarse calcifications,3 calcifications in the benign lesions were found both by micropure system and gray?scale ultrasound imaging;while in these malignant lesions,11 and 9 calcifications were visual?ized by micropure system and gray?scale ultrasound imaging,respectively. There was no significant difference between the two methods(P>0.05). For the micro?calcifications,8 and 2 calcifications were found in the benign lesions by micropure system and gray?scale ultrasound imaging,respec?tively;while 12 and 5 calcifications were visualized in the malignant lesions by micropure system and gray?scale ultrasound imaging,respectively. The micropure system method is more sensitive in micro?calcification detection compare to the traditional gray?scale ultrasound imaging method(P<0.05). Conclusion Micropure system can detect micro?calcifications and has a better visibility for micro?calcifications within the thyroid lesions, which can be applied in early thyroid cancer diagnosis.