A Clinical Study on Coenzyme Q10(Neuquinon(R)) in the Treatment of Congestive Heart Failure
Korean Circulation Journal
;
: 17-22, 1979.
Artículo
en Coreano
| WPRIM
| ID: wpr-60302
ABSTRACT
Coenzyme Q is concentrated in Golgi apparatus membranes and mitochondria, but not in other membranes. Although it is difficult to prove the metabolic action of coenzyme Q administered exogenously in clinical cases, the effect of this substance can be evaluated by criteria based on clinical findings. In an attempt to evaluate the effect of coenzyme Q for the treatment of 67 patients(male 26 cases, female 41 cases) of congestive heart failure, we administered Coenzyme Q1030mg daily for 4 to 8 weeks. Most of them were valvular heart disease(74.6%) and hypertension (14.9%). Clinical effects were evaluated at least 4 weeks later by the criteria using a scoring method of severity of congestive heart failure which was devised by Ishiyama, etc. In summary, a definite effect was found in 13 cases(19%) and a mild effect was observed in 46 cases(69%). During treatment there were no significant side effects, and also no significant changes in heart rate and blood pressure.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Proyectos de Investigación
/
Presión Sanguínea
/
Ubiquinona
/
Estrógenos Conjugados (USP)
/
Aparato de Golgi
/
Corazón
/
Insuficiencia Cardíaca
/
Frecuencia Cardíaca
/
Hipertensión
/
Membranas
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Circulation Journal
Año:
1979
Tipo del documento:
Artículo
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