Clinical analysis of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis / 中国生化药物杂志

ABSTRACT

Objective To analyze effect of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis.Methods 90 patients with hip arthritis patients from January 2014 to July 2015 were randomly divided into observation group and control group.45 cases in each group.Control group was given Diprospan treatment, observation group was treated with articular injection of sodium hyaluronate combined with diprospan treatment.After 4 weeks of treatment,patients were followed up and recorded hip pain VAS score and WOMAC score, lipids and C-reactive protein levels, content changes in ESR and TNF-α.Results The patients after hip pain VAS score and WOMAC scores were better than control group(P<0.05).After observation group patients lipids and C-reactive protein were lower than control group(P<0.05).After treatment ESR and TNF-αof observation group were lower than control group’s(P<0.05).Conclusion Intra-articular injections of sodium hyaluronate combined with diprospan in treatment of hip arthritis has definite clinical effect.