Extraction Technology Optimization of Total Flavonoids in Geum Aleppicum by Box-Behnken Design and Response Surface Methodology / 中国药师
China Pharmacist
;
(12): 241-243,250, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-603471
ABSTRACT
Objective:
To analyze and optimize the extraction technology of Geum aleppicum by Box-Behnken design and response surface methodology.Methods:
With the content of total flavonoids as the index, the effects of three factors including the solvent-solid ratio, ethanol concentration and extraction time on the content of total flavonoids were studied by single factor experiment, and the ex-traction technology was optimized by Box-Behnken design and response surface methodology.Results:
The optimal extraction condi-tions of Geum aleppicum were as followsthe solvent-solid ratio was 4. 2, the ethanol concentration was 50% and the extraction time was 80 min. Under the above conditions, the average yield was 12. 590 0 mg·g-1 .Conclusion:
Optimizing extraction technology of the total flavonoids in Geum aleppicum by Box-Behnken design and response surface methodology is reasonable, and the mathematical mod-el is consistent with the experimental data, which has good predictability.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Chino
Revista:
China Pharmacist
Año:
2016
Tipo del documento:
Artículo
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