The regulatory role of LiCl in microbial suppurative keratitis / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 478-479,481, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-603658
ABSTRACT
Objective To explore the role of LiCl in microbial suppurative keratitis .Methods Western-blot assay was used to detect the efficacy of LiCl .Inflammatory cytokine levels were examined using Real-time PCR .Cell apoptosis was detected by using TUNEL and flow cytometry assays .Results LiCl promoted corneal resistance to PA infection .Real-time PCR data showed that LiCl enhanced IL-10 expression ,but suppressed TNF-expression .TUNEL and flow cytometry data showed that LiCl promoted the apoptosis of infiltrating cells .Conclusion LiCl promoted host resistance against microbial suppurative keratitis ,via regulating in-flammatory cytokine expression and cell apoptosis .
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Laboratory Medicine
Año:
2016
Tipo del documento:
Artículo
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