High risk factors of progressive cerebral contusion and its correlation with prognosis in patients with brain ;contusion and laceration / 中国基层医药

ABSTRACT

Objective To study the risk factors of progressive cerebral contusion and laceration in patients with brain contusion and laceration,and to analyze the correlation between the prognosis of brain contusion and lacera-tion.Methods 128 patients with cerebral contusion and laceration were selected,and the patients were divided into the progress group (68 cases)and the non progress group (60 cases)according to the results of CT examination in 24h.Application of single factor and multiple factor Logistic regression analysis to analyze the risk factors of progres-sive cerebral contusion and laceration.And analyzed the related factors of the prognosis of patients.Results The admission GCS score,site of injury,cerebral contusion and laceration of volume,midline shift,with a skull fracture, complicated with subarachnoid hemorrhage,complicated with subdural hematoma,diabetes mellitus and D dimer level in the progress group and non progress group were significantly different (χ2 =9.336,P =0.009;χ2 =18.486,P =0.001;t =2.889,P =0.000;t =2.684,P =0.015;χ2 =16.164,P =0.000;χ2 =10.824,P =0.001;χ2 =8.667, P =0.003;χ2 =8.667,P =0.003;χ2 =10.824,P =0.001;t =2.842,P =0.000).Patients were followed up for 6 months,the mortality rate of the progress group was 11.76%,which was significantly higher than 1.67% in the non progress group (χ2 =4.972,P =0.026).Logistic regression analysis showed that admission GCS score,injury loca-tion,cerebral contusion and laceration of volume,complicated with subarachnoid hemorrhage,diabetes mellitus and D dimer level were risk factors of cerebral contusion and fracture trauma patients occurred in brain contusion and lacera-tion (OR =0.128,1.894,0.187,37.324,42.974,1.224,P =0.014,0.010,0.028,0.018,0.008,0.042,all P <0.05).Logistic regression analysis showed that the GCS score,the site of injury,the volume of brain contusion,the combination of subarachnoid hemorrhage and progressive brain contusion and laceration of brain contusion and lacera-tion were the prognostic factors (OR =0.133,1.124,0.208,34.321,41.964,P =0.018,0.014,0.025,0.018, 0.005,all P <0.05 ).Conclusion Admission GCS score,injury location,cerebral contusion and laceration of volume,complicated with subarachnoid hemorrhage,diabetes mellitus and D dimer level are risk factors of cerebral contusion and laceration happened progressive cerebral contusion and laceration,admission GCS score,site of injury, cerebral contusion and laceration of volume,complicated with subarachnoid hemorrhage and progressive cerebral con-tusion and laceration of brain contusion and laceration of prognostic factors,clinical should pay more attention to it.