Expression Pattern of Immunoproteasome Subunits in Human Thymus
Immune Network
;
: 285-288, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-60577
ABSTRACT
The expression pattern of immunoproteasomes in human thymus has not been analyzed but may have important consequences during thymic selection. Here we examined the expression patterns of immunoproteasome subunits in fetal and adult thymic tissues by immunohistochemistry and found that all three subunits are expressed in both cortical and medullary stromal cells. These data suggest that thymic selection in human can be affected by peptide repertoires generated by immunoproteasomes.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Timo
/
Inmunohistoquímica
/
Células del Estroma
Límite:
Adulto
/
Humanos
Idioma:
Inglés
Revista:
Immune Network
Año:
2009
Tipo del documento:
Artículo
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