Observation of clinical effect of glucocorticoid and hyperbaric oxygen therapy on thehigh-frequency and diminishing sudden deafness / 重庆医学

ABSTRACT

Objective To investigate the curative effect of glucocorticoid and hyperbaric oxygen therapy on the high-frequency and diminishing sudden deafness.Methods A total of 260 patients with high-frequency and diminishing sudden deafness were divided into hormone group(n=110),hyperbaric oxygen group(n=80) and routing group(n=70,ginaton 87.5 mg+5% GS 250 mL static drops static drops,intramuscular injection of vitamin B1 1.5 mg+cobamamide 0.1 g and 2% lidocaine 10 mL+5% GS 250 mL static drops).The first two groups were added oral prednison and hyperbaric oxygen therapy on the basis of therapy of routing group.The effect of comparison analysis was conducted after 10 days of treatment according to the course of disease which was less than that of or equal to 7 days or greater than 7 days.Results The overall curative effect of hormone group and hyperbaric oxygen group was better than that of routing group,and the difference was statistically significant (P<0.05).During the whole course of disease,the difference of therapeutic effect between routing group and the other two groups was statistically significant(P<0.05).Conclusion The glucocorticoid and hyperbaric oxygen therapy both have really curative effect on high-frequency and diminishing sudden deafness.