Effect analysis of esculin and digitalisglycosides eye drops on asthenopia caused by presbyopia / 中国医师杂志

ABSTRACT

Objective To investigate the efficacy of Esculin and Digitalisglycosides eye drops on asthenopia caused by presbyopia.Methods A total of 120 cases with asthenopia caused by presbyopia was randomly divided into two groups.The observation group (n =60 cases) was treated with Esculin and Digitalisglycosides eye drops,and the control group (n =60 cases) was treated with Naphazoline Hydrochloride,Chlorphenamine Maleate and Vitamin B12 eye drops,1 drop into each eye 3 times daily for 1 month.The symptoms of asthenopia,visual acuity,refraction,intraocular pressure,and safety evaluation were compared between two groups.Results Fifty seven cases in the observation group and 55 cases in the control group were observed after removal of data shedding cases.After treatment,asthenopia in both groups was significantly improved,observation group was significantly higher than control group (P ＜ 0.05).There was no statistical significance (P ＞ 0.05) between two groups after treatment in visual acuity,refraction,intraocular pressure and safety evaluation.Conclusions Esculin and Digitalisglycosides eye drops can effectively relieve symptoms of asthenopia caused by presbyopia,which is safe and convenient.It can be used in the clinical future.