Efficacy and safety of ginkgo biloba extract tablets combing with Butyphthalide to alzheimer disease / 中国生化药物杂志

ABSTRACT

Objective To observe efficacy and safety of ginkgo biloba extract tablets combing with butyphthalide to alzheimer disease(AD). Methods 72 patients with AD in our hospital from January 2015 -April 2016 were selected,and randomly divided into observation group and control group,36 cases in each groups..Two groups were given butylphthalide treatment,and observation group were given plus ginkgo biloba extract tablets. Results Afte treatment,effective rate of observation group was 86.11%,higher than control group 63.89%(P<0.05).Correlation scale score and plasma NO,serum VEGF and MDA level of observation group were better than control group(P<0.05).In adverse reaction,compared with observation group 8.33%,control group was 13.89%. Conclusion Ginkgo biloba extract tablets can improve the therapeutic effect of alzheimer disease and have less adverse reactions.