The research progress of acid sphingomyelinase and renal diseases / 中国医师杂志

ABSTRACT

Acid sphingomyelinase (ASMase),an important enzyme for production of ceramide has been reported to be involved in the regulation of cell and organ functions and has been implicated in the development of different diseases such as diabetes,hearty disease,liver and kidney diseases.Diabetic nephropathy is a common complication of diabetes.It was found that ASMase has been closely associated with the development renal disease.Hence,it is of great importance to study the impact of ASMase on renal diseases.