Multimodality Evoked Potentials in Amyotrophic Lateral Sclerosis

ABSTRACT

Twenty-one patients with amyotrophic lateral sclerosis were studied with visual, brain stern auditory and sornatosensory evoked potentials. Median nerve sensory evoked poten tials were recorded in 18 patients, showing prolonged absolute or interwave latencies in 5 pafients and no consistent wave forrnation in a patient. Posterior tibial nerve sensory evoked potentials were recorded in 16 patients, showing prolonged absolute or interwave latencies in 4 patients and no consistent wave formation in a patient. P1 absolute latency and arnplitude of VEP, I-III, III-V and I-V interpeak latencies of BAEP were withi normal lirnits in all ALS patients. These results suggest a pathological slovwing of conduction along the central sensory pathways in amyotrophic lateral sclerosis.