Progress on breast cancer research in patients aged 25 years and younger / 中国肿瘤临床

ABSTRACT

Breast cancer in younger patients exhibits stronger invasiveness and poorer outcomes compared with that in elders. Cut-off for young age remains unclear, and its basis as prognostic factor representing a continuous variable requires further investigation. Preg-nancy-associated breast cancer in young patients also possesses unique biological features. In this review, we define breast cancer di-agnosed in patients below 25 years old as very young breast cancer and summarize recent studies based on genetic factors, clinicopa-thology, prognostic characteristics, and pregnancy-associated breast cancer to assist in management of very young breast cancer pa-tients.