Imaging methods and characters of fetal spinal cord development / 中国组织工程研究

ABSTRACT

BACKGROUND:Fetal congenital malformation is an important cause of perinatal fetal death,in which neural tube defects (NTDs) in prenatal deformity screening is more common.In recent years,with the deterioration of environment and the increase in the number of elderly maternal,patients with NTDs are increasing,bringing serious social and family economic burden.Therefore,modern imaging methods are used to provide theoretical basis for prenatal screening NTDs.OBJECTIVE:To study the development of fetal spinal cord morphology by means of imaging,so as to provide reference for the diagnosis of prenatal screening.METHODS:A computer-based retrieval of CNKI,WanFang,VIP,CBM and PubMed databases was conducted for the report on the development of fetal spinal cord from 1959 to 2017,and their different imaging studies were summarized.RESULTS AND CONCLUSION:In view of the impact of radiation on pregnant women and the fetus,in order to better imaging,for different organizational structures using different detection methods.(1) X-ray and CTdue to radiation damage to pregnant women and fetuses,they are only used for the cadaveric spine ossification center development,X-ray has been abandoned,and CT has not seen a live report.(2) Ultrasound is easy to operate,and non-invasive for pregnant women and fetuses,which is the preferred method of inspection.(3) MRI,as an important supplement means of ultrasound,can provide imaging basis for the prenatal assessment of fetal spinal cord development and diagnosis of related diseases.(4) Noticeably,harm of radiation to fetus should be considered.