The Significance of Detecting Serum CRP, Myocardial Enzymes, Liver Function Index in Pediatric Patients with Rotavirus Infectious Diarrhea / 现代生物医学进展

ABSTRACT

Objective:To explore the significance of detecting serum CRP,myocardial enzymes,liver function index in pediatric patients with rotavirus infectious diarrhea.Methods:110 pediatric patients with rotavirus infectious diarrhea and 85 age-matched patients with bacterial infectious diarrhea who were both treated in our hospital from January,2014 to May,2016 were enrolled in the present study.Another 20 healthy patients who had physical examination in our hospital were considered as control group.The differences of serum CRP,IL-6,hs-cTnT,CK,CL-MB,AST,ALT level and the incidence of parenteral injury were compared.Results:The incidence rate of lower respiratory tract infectivity,rash,myocardial damage and hepatic injury in RV group were significantly lower than the bacterial infectious group (P＜0.05),the level of serum CRP,IL-6 in RV group and bacterial infectious group were significantly higher than the control group,and those of RV group were significantly lower than bacterial infectious group (P ＜0.05);the level of hs-cTnT,CK,CL-MB,AST,ALT in RV group were significantly higher than bacterial infectious group and control group (P＜0.05),and those indexes of bacterial infectious group were no significantly differences compared with healthy control (P ＞ 0.05).Conclusion:The combined detection of serum CRP,myocardial enzyme and liver function indexes were of certain significance in the early distinguishing diagnosis of bacterial infectious diarrhea from rotavirus infectious diarrhea.