Study on the effect of psychological intervention combined with preoperative chemotherapy with gefitinib on elderly patients with non- small cell lung cancer after localized resection of lung cancer / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical efficacy of psychological intervention and gefitinib in the treatment of elderly patients with non-small cell lung cancer with limited pulmonary resection. Methods The control group were all treated with limited pulmonary resection. Preoperative chemotherapy was given to gefitinib. The study group was given psychological intervention during the preoperative chemotherapy on the basis of the control group. Results The resection rate in the study group was 93.55％, while in the control group was 74.19％, the difference in the two groups was statistically significant(P<0.05). The transfer rate was 3.23％ and the recurrence rate was 3.23％ in the control group, which was significantly lower than those in the control group the transfer rate of 19.35％, the recurrence rate of 16.13％. 1 years survival rate in the study group 80.65％ was significantly higher than that in the control group 64.52％, the difference was statistically significant(P<0.05). Conclusion On the basis of routine preoperative application of gefitinib combined with local excision treatment, the elderly patients with non-small cell lung cancer with psychological intervention measures can make them achieve more ideal effect and prognosis.