Relationship Between Blood Triglyceride Level and Brachial-ankle Pulse Wave Velocity in Relevant Population / 中国循环杂志

ABSTRACT

Objective: To investigate the relationship between blood triglyceride (TG) level and brachial-ankle pulse wave velocity (baPWV) in relevant population. Methods: A total of 22622 participants in Kailuan area were enrolled and divided into 4 ranks Stroke rank, n=5219, Aged rank n=1754, Pregnancy hypertension Rank, n=1561and Peripheral vascular diseases rank, n=14088. All participants finished baPWV examination. The relationship between TG and baPWV was studied by partial correlation analysis, the impact of TG on baPWV was assessed by multivariate linear regression and multivariate Logistic regression analysis. Results: There were 21713 subjects finally enrolled for cohort study and 909 subjects excluded for missing TG information. With elevated TG levels, the average baPWV and the detection rate of baPWV≥1400 cm/s showed the increasing trend. Partial correlation analysis presented that TG level was positively related to baPWV, r=0.235; with adjusted age and gender, TG was still positively related to baPWV, r=0.080. Logistic regression analysis indicated that with other adjusted confounding factors, compared with the first quartile of TG, the second quartile, third quartile and fourth quartile of TG were the risk factors for baPWV≥1400 cm/s, OR=1.161, 95% CI (1.035-1.302), OR=1.312, 95% (1.165-1.476) and OR=1.652, 95% CI (1.463-1.865) respectively. Conclusion: Blood TG level was positively and independently related to baPWV in relevant population.