Role and mechanism of thrombin in white matter injury after intracerebral hemorrhage / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 449-453, 2017.
Artículo
en Chino
| WPRIM
| ID: wpr-617822
ABSTRACT
Intracerebral hemorrhage accounts for about 10%-30% of all stroke types.It is characterized by rapid onset, rapid progress, varied clinical symptoms, high morbidity and mortality, and poor prognosis.After the intracerebral hemorrhage, various inflammatory mediators result in white matter lesions and cognitive impairment.Thrombin acting on thrombin receptors at low concentration induces neuroprotection and at high concentration causes brain injury.This article reviews the role and mechanism of thrombin in white matter injury after intracerebral hemorrhage.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
International Journal of Cerebrovascular Diseases
Año:
2017
Tipo del documento:
Artículo
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