Dose-response relationship and muscle relaxant residual induced by rocuronium in children with cleft lip and palate repair / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 708-711, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-618601
ABSTRACT
Objective:
To investigate the effects of rocuronium in the intravenous anesthesia in children with cleft lip and palate repair.Methods:
According to random number table,96 children with cleft lip and palate aged 1-3 years underwent general anesthesia for surgery were divided into 3 groups (n =32).The children in group A,B and C received intravenous injection of rocuronium at 0.6,0.9 and 1.2 mg/kg,respectively.The anesthesia effects were observed.Accelerometry (TOF-Watch(@) SX) was used to monitor neuromuscular transmission.Results:
Intubating conditions ranged from good to excellent in all children.The onset time of anesthesia in Group C was significantly shorter(P < 0.05),the duration of neuromuscular block was significantly longer in group C than in group A and B (P < 0.05).The recovery index in group C was significantly longer than that in group A and B (P < 0.05,A vs B,P > 0.05).Muscle relaxant residual incidence in group C was higher than that in group A and B (P < 0.05,A vs B,P > 0.05).Conclusion:
Rocuronium at 0.6 mg/kg or 0.9 mg/kg are effective for excellent tracheal intubation,with faster onset time and recovery time,low incidence of postoperative residual curarization(PORC) in children with cleft lip and palate repair.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Practical Stomatology
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS