Clinical curative effect analysis of Masquelet technique for treatment of infected single-bone defect of forearm / 局解手术学杂志

ABSTRACT

Objective To evaluate the clinical curative effect of Masquelet technique in treatment of infected single-bone defect of forearm.Methods The clinical data of 18 cases of forearm bone defect caused by bone infection in our department from January 2011 to June 2016 were retrospectively analyzed.All the patients received standard treatment of Masquelet technique with two stage.Radical debridement,bone defect filling with antibiotic PMMA bone cement, and internal fixation were accomplished at the first stage, and treatment of bone defect with autologous iliac bone graft were accomplished at the second stage after 6 to 8 weeks at the end of the first stage.The infection control,fracture healing and complications of the 18 patients were observed.Results There was no complications such as infection recurrence,bone resorption,plate screw loosening occured.The functional recovery of 18 cases in this group was evaluated according to the Anderson evaluation scale.The results were excellent in 9 cases,satisfactory in 6 cases,unsatisfactory in 3 cases,and no failure.The satisfactory rate was 83.33%.Conclusion Controlling infection with local release of antibiotics from PMMA bone cement implantation through Masquelet technique, inducing autogenous membrane structure in the bone defect area,and then transplanting autologous cancellous bone for bone defect reconstruction repair treatment are effective in the treatment of infected single-bone defect of forearm.