Investigation of epidemiology of HPV infection and its correlation with other diseases of reproductive system / 国际检验医学杂志

ABSTRACT

Objective To investigate epidemiology of human papillomavirus(HPV) infection in females of this area.Methods Hybrid technology was performed to detect HPV subtypes in 2 509 females with age of 16-79.ThinPrep cytology(TCT),leucorrhea routine examination and other detections were also performed.The detection results of HPV detection and the correlation between HPV infection and other diseases were analyzed.Results The overall prevalence of HPV was 13.9%,with 10.4% and 3.3% of high-risk and low-risk HPV prevalence respectively.The most common high-risk HPV types were 16,58,18,33 and 56 subtype,and the most common low-risk HPV types were 11,6 and 43 subtype.There were two peaks of HPV prevalence at age of 16-20 years and >55-60 years,and the single infection was prevalent.Compared with the healthy subjects,the HPV detection rate in patients with cervicitis and cervicitis/vaginitis were higher(P<0.05).In addition,the rate of HPV infection was higher in Ureaplasma urealyticum positive subjects than negative subjects(P<0.05).Conclusion The increasing detection rate of HPV,especially the high-risk subtype of 16,58 and 33,might be related to lower genital tract infection.