Analysis on the application value of brain natriuretic peptide levels in patients with hemorrhagic fever of seriously renal syndromes continuous renal replacement therapy / 中国生化药物杂志

ABSTRACT

Objective To observe and investigate b-type natriuretic peptide(BNP)levels in patients with hemorrhagic fever of seriously renal syndromes line of continuous renal replacement therapy(CRRT)application value.Methods From January 2015 to October 2015 were 48 cases of patients with hemorrhagic fever of seriously renal syndromes as the research object.Conservative treatment after 3 d better person to be included in the control group(24cases), no better continue CRRT(CRRT group, 24cases).Records in the two groups before the conservative treatment in patients with mean arterial pressure(MAP), albumin(propagated), hemoglobin(Hb), b-type natriuretic peptide(BNP)and a 24 h urine(24 h urine);Record after conservative treatment 3 d urea nitrogen, serum creatinine, BNP and 24 h urine(24 h urine).Compare the differences between the two groups of the clinical indicators.Results The control group with CRRT group propagated, urea nitrogen, serum creatinine, BNP-I, BNP-Ⅱ, 24 h urine-Ⅰ, 24 h urine-Ⅱ comparison, the difference had statistical significance (P<0.05).Conclusion The short term the 24 h urine after conservative treatment and BNP levels can better predict whether patients with hemorrhagic fever of Seriously renal syndromes should be line of CRRT.