ANTIVIRAL TESTS OF METHYLENE BLUE INJECTION ON VZV IN VITRO / 药物分析学报

ABSTRACT

Methylene blue injection has a stronger direct inactivation on VZV in vitro. When the injection was diluted from 116 to 1128, which was obvious (P＜0.01 and P＜0.05). The MIC was 1222, the IC50 was 1135 and IC90 was 177. The results of microcellculture method showed when the injection was diluted from 116 to 164, it also effectively inhibited the proliferation of VZV in WISH continuous cell-lines (P＜0.01 and P＜0.05). The MIC was 195, the IC50 was 145 and the IC90 was 121.