Mucous membrane pemphigoid

ABSTRACT

Mucous membrane pemphigoid is a group of putative autoimmune, chronic inflammatory, subepithelial blistering diseases predominantly affecting mucous membranes, characterised by linear deposition of IgG, IgA, or C3 along the epithelial basement membrane1. This variant of pemphigoid is rare and encompasses a heterogeneous group manifesting a varying constellation of oral, ocular, skin, genital, nasopharyngeal, oesophageal and laryngeal lesions. In severe cases, it may lead to blindness due to ocular involvement and may even be life threatening due to airway obstruction. We report a case of mucous membrane pemphigoid with oral and genital involvement.