Hypertriglyceridemia and Cardiovascular Diseases: Revisited
Korean Circulation Journal
;
: 135-144, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-62942
ABSTRACT
Residual cardiovascular risk and failure of high density lipoprotein cholesterol raising treatment have refocused interest on targeting hypertriglyceridemia. Hypertriglyceridemia, triglyceride-rich lipoproteins, and remnant cholesterol have demonstrated to be important risk factors for cardiovascular disease; this has been demonstrated in experimental, genetic, and epidemiological studies. Fibrates can reduce cardiovascular event rates with or without statins. High dose omega-3 fatty acids continue to be evaluated and new specialized targeting treatment modulating triglyceride pathways, such as inhibition of apolipoprotein C-III and angiopoietin-like proteins, are being tested with regard to their effects on lipid profiles and cardiovascular outcomes. In this review, we will discuss the role of hypertriglyceridemia, triglyceride-rich lipoproteins and remnant cholesterol on cardiovascular disease, and the potential implications for treatment stargeting hypertriglyceridemia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Triglicéridos
/
Enfermedades Cardiovasculares
/
Hipertrigliceridemia
/
Estudios Epidemiológicos
/
Ácidos Grasos Omega-3
/
Colesterol
/
Factores de Riesgo
/
Inhibidores de Hidroximetilglutaril-CoA Reductasas
/
Apolipoproteína C-III
/
Ácidos Fíbricos
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
Idioma:
Inglés
Revista:
Korean Circulation Journal
Año:
2016
Tipo del documento:
Artículo
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