Gene expression characteristic in human auricular cartilage tissue engineering
The Medical Journal of Malaysia
;
: 190-191, 2004.
Artículo
en Malayalam
| WPRIM
| ID: wpr-629960
ABSTRACT
This study was to assess collagen type II and collagen type I gene expression in tissue-engineered human auricular cartilage formed via tissue engineering technique. Large-scale culture expansions were transformed into 3D in vitro construct and were implanted subcutaneously on the dorsal of athymic mice. After 8 weeks, explanted construct was processed in the same manner of native cartilage to facilitate cells for gene expression analysis. Isolated cells from in vivo construct demonstrated expression of type II collagen gene comparable to native cartilage. This study verified that tissue-engineered auricular cartilage expressed cartilage specific gene, collagen type II after in vivo maturation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Cartílago
/
Expresión Génica
/
Células Cultivadas
/
Actinas
/
Senescencia Celular
/
Condrocitos
/
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
/
Colágeno Tipo I
/
Colágeno Tipo II
Idioma:
Malayalam
Revista:
The Medical Journal of Malaysia
Año:
2004
Tipo del documento:
Artículo
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