Application of Elisa technique for detection anti \ufffd?HLA antibodies after solid organ transplantation
Journal of Medical Research
;
: 40-44, 2007.
Artículo
en Vietnamita
| WPRIM
| ID: wpr-630
ABSTRACT
Background:
Anti \ufffd?HLA (Human Leukocyte Antigen) antibody is result of immunization in allotransplantation. Organ transplantation is one of the great scientific achievements of the medicine. However, it is difficult to have the perfect harmony of HLA group. Inevitable consequence is the graft will be eliminated by the immune process. In Vietnam, organ transplantation was a relatively new specialty and there was not much research on evaluation immune process after transplantation.Objectives:
To determine the rate of present of anti \ufffd?HLA antibody on transplant patients, and the role of post \ufffd?transplant anti \ufffd?HLA antibodies on long \ufffd?term graft function. Subjects andmethod:
ELISA technique was used to analysis 31 blood samples of 31 patients who were transplanted organs at 103 military hospital and Cho Ray hospital from May 2000 to July 2007. This was a retrospective and described cross-sectional study on theclinical records.Results:
The rate of anti \ufffd?HLA antibodies was 35.5%. The present of anti \ufffd?HLA antibodies of transplant patients had negative impact on graft function.Conclusion:
The detection of anti \ufffd?HLA antibodies by ELISA in the post transplant period may be a high confident and sensitive technique for follows up graft function.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ensayo de Inmunoadsorción Enzimática
/
Trasplante de Órganos
/
Antígenos HLA
/
Anticuerpos
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Idioma:
Vietnamita
Revista:
Journal of Medical Research
Año:
2007
Tipo del documento:
Artículo
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