Influence of Diabetes Mellitus and Risk Factors in Activating Latent Tuberculosis Infection: A Case for Targeted Screening in Malaysia
The Medical Journal of Malaysia
;
: 467-472, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-630249
ABSTRACT
A review of the epidemiology of tuberculosis, its contributing risk factors (excluding HIV) and the role of screening latent tuberculosis infection in Malaysia was done. Despite the global and domestic decrease in prevalence rates of tuberculosis in the past decade, there is an alarming increase in the trend of non communicable diseases in the country. High prevalence rates of major risk factors leading to reactivation of tuberculosis were seen within the population, with diabetes mellitus being in the forefront. The rising numbers in the ageing population of Malaysia poses a further threat of re-emergence of tuberculosis in the years to come. Economically, screening of diabetic patients with comorbidities for latent tuberculosis infection (LTBI) using two major techniques, namely tuberculin sensitivity (TST) and Interferon gamma release assay tests (IGRA) could be a viable option. The role of future research in the detection of LTBI in the Malaysian setting might be necessary to gauge the disease reservoir before implementing prophylactic measures for high risk groups involved.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Factores de riesgo
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
The Medical Journal of Malaysia
Año:
2012
Tipo del documento:
Artículo
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