Idiopathic central precocious puberty: A case report / Philippine Journal of Obstetrics and Gynecology

ABSTRACT

Central precocious puberty is characterized by early pubertal changes, acceleration of growth velocity, and rapid bone maturation. It is a relatively rare disorder, with an incidence rate of about 15000-110000 individuals in the general population; it is more frequent in girls than in boys. This is a case of a 7 year-old female complaining of onset of menstruation. Physical examination revealed advanced pubertal changes of Tanner stage 4-5 for breast and stage 3 for pubis. Diagnostic evaluation revealed well developed internal genitalia, markedly elevated LH levels, advanced bone aging and a normal cranial MRI. Based on clinical and diagnostic evaluations, a diagnosis of idiopathic central precocious puberty was made and the patient was started on GnRha therapy. It is important to initiate therapy early in patients with central precocious puberty so as to prevent compromised adult height and psychosocial embarrasment