Effect of Metformin Therapy on Obese Nondiabetic Children with Hyperinsulinemia / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2004.
Article
en Zh
| WPRIM
| ID: wpr-639181
Biblioteca responsable:
WPRO
ABSTRACT
Objective To explore the efficacy and safety of metformin therapy on obese nondiabetic children with hyperinsulinemia.Methods Twenty-two obese nondiabetic children with hyperinsulinemia were divided into two groups:control group(dietary counseling and exercise) and treatment group(dietary counseling and exercise combined with metformin).The changes of body mass index(BMI),fasting glucose(FPG),fasting insulin(FINS),insulin resistance(HOMA-IR),2 h PG,2 h INS,total cholesterol(TC) and triglyceride(TG),before and after treatment were determined,and the findings were compared and analyzed.Results After treatment,there were significant differences in BMI,TC,FINS,HOMA-IR levels(P0.05),except the BMI(P
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WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Año:
2004
Tipo del documento:
Article