Inhibition Effect of Methylprednisolone on Inflammatory Response during Immature Myocardial Ischemia Reperfusion Injury / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
;
(24)1986.
Artículo
en Chino
| WPRIM
| ID: wpr-639866
ABSTRACT
Objective To study the effect of methylprednisolone on serum interleukin-1(IL-1),8,10 during immature myocardial ischemia reperfusion injury.Methods A total of 70 rats were randomly divided into 3 groupscontrol group(n=10),model group(n=30)and drug group(n=30).And the later 2 groups were observed at 0.5 h after ischemia and 2,4,8,12,24 h after reperfusion with 5 rats in each group and the control group were observed only at 12 h.The rat model of myocardial ischemia reperfusion injury(MIRI)was established.Morphology changes were observed and the levels of serum IL-1,8,10 were examined.Results Compared with model group,inflammatory response in drug group weaken clearly,IL-1,8 were lower(Pa
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Applied Clinical Pediatrics
Año:
1986
Tipo del documento:
Artículo
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